Category: Critical Care & Surgery / Organ Damage
Ischemia-reperfusion injury (IRI) is tissue damage caused when blood supply returns to tissue after a period of ischemia (lack of oxygen), leading to oxidative stress, inflammation, and cell death, particularly relevant in organ transplantation and myocardial infarction.
Common complication in organ transplantation (affecting nearly all organs to varying degrees), myocardial infarction, stroke, and major surgeries (Source: Nature Reviews Nephrology, 2018).
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