Can you reach diabetes remission if you aren't overweight?

Early research suggests some people can. In the small ReTUNE study, 14 of 20 people with type 2 diabetes and a BMI under 27 were in remission after 12 months of stepwise weight loss. It is one small study, and it can't tell you what will happen for you.

Most of what's written about diabetes remission is about people with obesity. That leaves out a lot of people, especially South Asians, who tend to develop type 2 diabetes at a much lower weight. In a study of 1.4 million adults in England, a South Asian person with a BMI of about 24 had the same diabetes risk as a white person with a BMI of 30 (Caleyachetty et al., Lancet Diabetes & Endocrinology, 2021).

If your doctor has told you your weight looks fine, it's reasonable to wonder whether remission applies to you at all. The early research is encouraging.

What the word means

Doctors use a specific definition: an HbA1c below 6.5% (48 mmol/mol), at least three months after stopping all glucose-lowering medicines (Riddle et al., Diabetes Care, 2021). They say remission instead of cure because sugar can rise again, so an HbA1c check at least once a year is still needed.

What the studies found

In the ReTUNE study in Newcastle, 20 people with type 2 diabetes and a BMI under 27 lost weight in steps of about 5%. After 12 months, 14 of the 20 were in remission. The group's average BMI went from 24.8 to 22.5, and the fat in their livers fell to normal levels (Taylor et al., Clinical Science, 2023).

A second small trial, STANDby, followed South Asian adults in the UK who had been diagnosed within the last four years. They used a supervised formula diet of about 850 calories a day for three to five months, and 10 of the 23 who started reached remission, similar to rates seen in white groups (Sattar et al., Lancet Regional Health Southeast Asia, 2023). Those participants had an average BMI of 32, so this trial tells us about South Asian adults in general, and ReTUNE is the one that speaks to diabetes at a lower weight.

Both studies are small, and neither tells you what will happen for you. Remission is more likely when diabetes was found recently and insulin hasn't been started. In the larger DiRECT trial, it lasted mainly for people who kept the weight off.

A sensible way to start

Get a baseline HbA1c and liver tests, then repeat them at three months and again at six. A glucose sensor can fill the gap in between by showing which meals and habits move your numbers within days.

If you take insulin or tablets such as sulfonylureas, eating much less can push your sugar too low. Talk to your doctor before cutting calories sharply or stopping any medicine, so doses can be reduced safely.

If you've been told weight isn't your problem and you aren't sure what to do next, talk to one of our experts or coaches.

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Common questions

Can you reach remission if you aren't overweight?

Early research suggests some people can. In the small ReTUNE study, 14 of 20 people with a BMI under 27 were in remission after 12 months. It is one small study.

What counts as diabetes remission?

An HbA1c below 6.5% (48 mmol/mol), measured at least three months after stopping all glucose-lowering medicines.

Is it safe to cut calories sharply if I take diabetes medicine?

Insulin and tablets such as sulfonylureas can push your sugar too low if you eat much less. Talk to your doctor first so doses can be reduced safely.

Sources

  1. Caleyachetty R et al. Ethnicity-specific BMI cutoffs for obesity based on type 2 diabetes risk in England. Lancet Diabetes Endocrinol 2021
  2. Riddle MC et al. Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes. Diabetes Care 2021;44(10):2438-2444
  3. Taylor R et al. The ReTUNE study. Clinical Science 2023
  4. Sattar N et al. The STANDby trial. Lancet Regional Health Southeast Asia 2023
  5. Lean MEJ et al. Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of DiRECT. Lancet Diabetes Endocrinol 2019;7(5):344-355

Last updated: 2026-11-09. Educational information, not medical advice. Talk to your doctor before changing your treatment.