Eversense 365-Day Implantable CGM — FDA Approved February 2025

Type: device

Status: FDA Approved — Commercially Available

Developer: Senseonics

Breakthrough Summary

The Eversense 365 is the first fully implantable CGM lasting a full year. FDA approved February 2025. Fluorescence-based sensor implanted in the upper arm during a brief in-office procedure. Real-world data shows MARD of 8.5%, comparable to transcutaneous sensors, with 99.5% data availability and no adhesive-related skin issues.

Mechanism of Action

A polymeric sensor coated with glucose oxidase and fluorescent indicator molecules is implanted subcutaneously. Glucose binds to the indicator, modulating fluorescence measured by an external transmitter worn over the sensor. Data streams to a smartphone app.

Year: 2025